Preheat oven to 350 degrees F. Mix together Italian seasoning, garlic powder, onion powder, pepper, and salt in a small bowl. Apply the mixture to chicken breasts and place on a greased baking sheet. Bake chicken until fully cooked.
Chop bacon into pieces and slice cooked chicken into approximately 1-inch pieces. In a large mixing bowl, pour in alfredo sauce, chicken, bacon, ½ cup mozzarella cheese and prepared penne pasta. Stir so that all components are coated in sauce and pour into a greased 9×12 casserole dish. Top with remaining mozzarella and sprinkle on dried parsley.