Preheat oven to 400F and lightly spray a 1 ½ quart casserole dish with cooking spray.
In a large skillet over medium-high heat cook burger until no longer pink inside; drain any excess fat. Stir in the Alfredo sauce, Worcestershire sauce, and tomato. Bring mixture to a boil, reduce heat to simmer, and continue cooking for 5 minutes; pour meat mixture into casserole dish.
Sprinkle the cheese over the top and arrange the biscuits on top of the cheese.
Bake for 10 minutes or until biscuits is nicely browned.